Mandibulo-facial dysostosis (Treacher Collins syndrome).

Mandibulo-facial dysostosis has been described with increasing frequency in recent years. Once known it is readily recognized and may be more common than is sometimes imagined. We describe in this article a case seen in a newlyborn infant who died at the age of 21 months and in whom careful dissections were made of the facial region. The infant (A.R., 456/1954) was admitted to the Royal Aberdeen Hospital for Sick Children at the age of 2 weeks He would take several drachms of his feed, then fall asleep; there was no vomiting and the bowels moved well. The child at 2 weeks weighed 5 ib. 7 oz. No abnormalities were found about the heart or lung. No masses were felt in the abdomen. On admission it was noted that the baby was a 'bird-like crature with rather curious eyes and a receding chin'; the nostrils were sonmwhat small; there was hypoplasia of the malar bones; the ears were rather low set with some failure of cartilage development, and appeared too big; the tongue seemed a little lare and was held towards the back of